SNDX · Syndax Pharmaceuticals, Inc.

NASDAQ NMS - GLOBAL MARKET - Real Time Price • USD

Syndax Pharmaceuticals Inc (SNDX)

NASDAQ NMS - GLOBAL MARKET Biotechnology
Move probability → Options chain →
$13.64 -2.90 (-17.53%)
● Market open
DAY'S RANGE $13.64
$13.49 $14.66
52-WEEK RANGE $13.64
$12.99 $25.59

What's happening

Deterministic template sentences filled in from the same sourced figures shown elsewhere on this page -- not an AI-written summary, no live model call.

Key Statistics

Market Cap$1.48B
P/E (TTM1)—
EPS2 (TTM)$-2.52
Div Yield—
Beta30.39
Volume143,511
Open14.64
Prev Close16.54
Bid / Ask13.59 / 13.62
Next Earnings 2026-10-29

Analyst Recommendations

Strong buy 8 Buy 10 Hold 1 Sell 0 Strong sell 0

Aggregate ratings for 2026-09-01 (19 analysts polled by Finnhub) — consensus count.

Performance Overview (Trailing returns vs S&P 500 benchmark)

YTD RETURN
SNDX -19.13%
vs S&P 500 -33.31%
1-YEAR RETURN
SNDX +4.88%
vs S&P 500 -11.13%
6-MONTH RETURN
SNDX -31.05%
3-MONTH RETURN
SNDX -28.04%

Valuation Measures & Ratios

Enterprise Value4$1.72B
Forward P/E5—
PEG Ratio6—
Price / Sales (TTM1)5.84
Price / Book7128.29
EV4 / Revenue6.83
EV4 / EBITDA1525.79
Profit Margin-87.52%
Operating Margin-76.98%
Return on Equity (ROE8)-372.94%
Return on Assets (ROA9)-39.11%
Avg Volume (3M)1,798,900
Quarterly history (5 periods)
Measure Jun '26Mar '26Sep '25Jun '25Mar '25
Market cap $1.96B $2.08B $1.33B $811.5M $1.06B
P/E -8.73 -7.99 -4.43 -2.63 -3.44
Price/Sales 8.85 12.31 11.47 10.97 29.52
Price/Book 129.88 49.92 11.56 5.16 4.95
EV/Revenue 8.92 13.61 13.27 13.97 34.57
ROE -1487.50% -624.86% -261.23% -196.21% -143.88%
ROA -31.92% -55.02% -54.65% -51.81% -48.30%

Trailing-twelve-month ratios computed from SEC EDGAR quarterly figures and historical daily close prices (Alpaca). Diluted shares are derived from Net income ÷ EPS (diluted) for each quarter, not separately reported. Forward P/E/PEG unavailable (no free data source).

Glossary — what these abbreviations mean
1. TTM
Trailing twelve months — the sum of the last four reported quarters, not a calendar year or the single latest quarter.
2. EPS
Earnings per share — net income divided by diluted shares outstanding.
3. Beta
A stock's historical volatility relative to the overall market. Above 1 means it has moved more than the market; below 1, less.
4. EV (Enterprise Value)
Market cap plus total debt minus cash — roughly what it would cost to buy the whole company, debt included.
5. Forward P/E
Price divided by analysts' estimated earnings for the next 12 months, instead of trailing actual earnings.
6. PEG Ratio
P/E divided by expected earnings growth rate. A lower number can indicate a stock is cheap relative to how fast it's expected to grow.
7. Price / Book
Share price divided by book value (assets minus liabilities) per share.
8. ROE
Return on equity — net income divided by shareholders' equity, a measure of how efficiently a company turns equity into profit.
9. ROA
Return on assets — net income divided by total assets, a measure of how efficiently a company turns assets into profit.
10. MRQ
Most recent quarter — the single latest reported period, as opposed to TTM. The Financials section's "Quarterly" view below shows MRQ-style figures.
11. YoY
Year over year — percent change versus the same period one year earlier, used for growth figures like those on Compare cards and the Screener.

Short Interest

Shares Short18,234,880
Change from Prior Settlement-11.74%
% of Float—
Days to Cover (Short Ratio)8.47

Source: FINRA Rule 4560 consolidated short interest, settlement date 2026-09-30. Reported bi-monthly with a reporting lag — not real-time.

Quotes and the 1-day extended-hours chart: Yahoo Finance. Longer historical charts: Alpaca (IEX feed) — real-time but IEX-only volume (~2.5% of consolidated market volume). Fundamentals + earnings: Finnhub.

Price history

Events

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Technical signal summary

Calculating from the latest year of daily price history…

Calculating…
Show Technical Analysis Breakdown ▾ 10 Indicators

Not investment advice — read several signals together.

Indicators None active

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Starter sets
Trend
Oscillators
Volume/volatility
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History limited by data provider; markers are heuristics, not signals.

Peer and sector context

No reviewed peer group is available for this symbol.

Balanced evidence

A deterministic summary of sourced facts—not an AI verdict.

Potential strengths

Potential concerns

Rule-based facts only; absence from either side is not evidence, and this is not a recommendation.

Financials

Income statement

Line item Jun '26Mar '26Sep '25Jun '25Mar '25Sep '24Jun '24Mar '24
Revenue $72.8M $64.9M $45.9M $38.0M $20.0M $12.5M $3.5M $0
Operating income -$40.0M -$34.2M -$57.4M -$69.4M -$83.8M -$89.6M -$74.2M -$79.5M
Net income -$49.4M -$42.7M -$60.7M -$71.8M -$84.8M -$84.1M -$68.1M -$72.4M
EPS (diluted) $-0.55 $-0.48 $-0.70 $-0.83 $-0.98 $-0.98 $-0.80 $-0.85
EPS (basic) $-0.55 $-0.48 $-0.70 $-0.83 $-0.98 $-0.98 $-0.80 $-0.85
Operating margin -$55 -$53 -$125 -$183 -$418 -$717 -$2.1K —

Balance sheet

Line item Jun '26Mar '26Dec '25Sep '25Jun '25Mar '25Dec '24Sep '24
Total assets $703.7M $472.7M $529.7M $551.8M $596.1M $640.7M $724.8M $425.8M
Total liabilities $688.6M $431.0M $465.1M $436.4M $438.7M $425.6M $436.7M $59.4M
Stockholders' equity $15.1M $41.6M $64.6M $115.4M $157.4M $215.1M $288.1M $366.4M
Total current assets $675.0M $471.2M $528.1M $529.8M $531.7M $548.8M $603.1M $414.8M
Total current liabilities $99.7M $86.2M $120.1M $114.2M $113.0M $94.6M $103.5M $59.4M
Cash & equivalents $336.5M $130.9M $134.9M $116.8M $108.6M $154.0M $154.1M $133.0M

Cash flow

Line item Jun '26Mar '26Dec '25Sep '25Jun '25Mar '25Dec '24Sep '24
Operating cash flow -$30.3M -$50.3M -$69.5M -$70.5M -$87.8M -$95.2M -$57.4M -$62.3M
Investing cash flow -$16.9M $38.4M $81.6M $72.4M $41.9M $94.1M -$269.0M $86.8M
Financing cash flow $252.8M $7.9M $5.9M $6.3M $551.0K $930.0K $347.4M $3.1M
Free cash flow — — -$69.7M — — — -$57.4M —
Capital expenditures — — $187.0K — — — $0 —
Depreciation & amortization — — — — — — — —

Source: SEC EDGAR XBRL filings (10-Q/10-K), as originally tagged by the company. Quarterly cash flow is reconstructed by de-cumulating fiscal-year-to-date figures (how cash flow is tagged in 10-Qs); other quarterly lines are reported directly.

Institutional holders

SEC Form 13F filers holding SNDX as of the latest reported quarter. 13F only covers investment managers with $100M+ in assets — this is not a complete ownership picture, and does not include insiders (see Recent SEC filings below) or non-13F-eligible holders.

Source: Business Quant SEC Form 13F · report period 2026-06-30 · 30 filers

Held by These Filers90.2%
Shares Outstanding88,991,317
FilerSharesValue% OutQtr ChangeFiled
BlackRock, Inc. 9,020,006 $197.2M 10.14% +9.3% 2026-08-07
Kynam Capital Management, LP 8,050,959 $176.0M 9.05% +0.0% 2026-08-14
Goldman Sachs Group Inc 5,861,265 $128.1M 6.59% +17.3% 2026-08-14
State Street Corp 5,658,424 $123.7M 6.36% +27.7% 2026-08-07
Bank Of America Corp /De/ 4,045,094 $88.4M 4.55% -4.8% 2026-08-14
VANGUARD CAPITAL MANAGEMENT LLC 3,927,892 $85.9M 4.41% +2.8% 2026-06-30
DEERFIELD MANAGEMENT COMPANY, L.P. 3,779,900 $82.6M 4.25% +0.0% 2026-08-14
Eversept Partners, LP 2,798,210 $61.2M 3.14% -3.0% 2026-08-14
GEODE CAPITAL MANAGEMENT, LLC 2,584,136 $56.5M 2.90% +19.8% 2026-08-12
Hood River Capital Management LLC 2,564,279 $56.1M 2.88% +8.9% 2026-08-06
KINGDON CAPITAL MANAGEMENT, L.L.C. 2,500,000 $54.6M 2.81% +0.0% 2026-08-14
Franklin Templeton Inc 2,286,499 $50.0M 2.57% +6.3% 2026-08-04
MILLENNIUM MANAGEMENT LLC 2,053,960 $44.9M 2.31% +929.4% 2026-08-14
VANGUARD PORTFOLIO MANAGEMENT LLC 1,921,796 $42.0M 2.16% +10.6% 2026-06-30
UBS Group AG 1,893,750 $41.4M 2.13% +64.2% 2026-08-13
Elmind Capital, LP 1,855,000 $40.6M 2.08% +0.0% 2026-08-14
BNP Paribas Asset Management Holding S.A. 1,790,173 $39.1M 2.01% +3.3% 2026-08-12
Candriam S.C.A. 1,696,040 $37.0M 1.91% +83.3% 2026-08-13
Soleus Capital Management, L.P. 1,628,039 $35.6M 1.83% -5.7% 2026-08-11
TWO SIGMA INVESTMENTS, LP 1,578,125 $34.5M 1.77% -0.1% 2026-08-07
ORBIMED ADVISORS LLC 1,542,000 $33.7M 1.73% +60.2% 2026-08-14
Nuveen, LLC 1,364,575 $29.8M 1.53% -8.7% 2026-08-11
MPM BioImpact LLC 1,333,523 $29.2M 1.50% -0.5% 2026-08-14
Aisling Capital Management LP 1,316,806 $28.8M 1.48% +0.0% 2026-08-13
Woodline Partners LP 1,250,760 $27.3M 1.41% +0.0% 2026-08-14

Insider activity

Directors, officers, and 10%+ owners' reported transactions from SEC Form 4. A filing reports a transaction; it does not by itself explain why it happened.

Source: SEC EDGAR Form 4 filings · checked 25 most recent filings · covers 2025-05-16 to 2026-07-08

Recent transactions

  • Insiders have net sold 105,914 shares over the last 182 days, across 0 purchases and 5 sales.
  • Most recent: Metzger Michael A (Chief Executive Officer) — Option exercise of 32,375 shares on 2026-07-08.

Deterministic template sentences filled in from the SEC Form 4 figures in the tables below -- not an AI-written summary, no live model call.

Insider purchases & sales, last 6 months

Purchases (open market)0 sh(0 txns)
Sales (open market)105,914 sh(5 txns)
Net Shares-105,914

Counts only open-market purchases (code P) and sales (code S) — grants, option exercises, tax withholding, and gifts are excluded since they aren't a market buy/sell decision.

Insider roster

NameTitleMost Recent TransactionDateShares
Metzger Michael AChief Executive OfficerOption exercise2026-07-0832,375
Botwood Nicholas A.J.Head of R&D, CMOOption exercise2026-06-1231,235
Goldan Keith A.Chief Financial OfficerOpen market sale2026-06-011,177
Jarrett JenniferReporting personGrant / award2026-02-0424,000
Huber Martin H. Jr.Reporting personGrant / award2026-02-0424,000
Podlesak DennisReporting personGrant / award2026-02-0448,000
Rizo AleksandraReporting personGrant / award2026-02-0424,000
Katkin KeithReporting personGrant / award2026-02-0424,000
Legault PierreReporting personGrant / award2026-02-0424,000

Recent transactions

DateInsiderTitleTransactionSharesPrice
2026-07-08Metzger Michael AChief Executive OfficerOption exercise 32,375$6.38
2026-07-08Metzger Michael AChief Executive OfficerOpen market sale 32,375$24.24
2026-06-12Botwood Nicholas A.J.Head of R&D, CMOOption exercise 31,235$13.82
2026-06-12Botwood Nicholas A.J.Head of R&D, CMOOpen market sale 31,235$18.14
2026-06-11Botwood Nicholas A.J.Head of R&D, CMOOption exercise 22,515$13.82
2026-06-11Botwood Nicholas A.J.Head of R&D, CMOOpen market sale 34,280$18.00
2026-06-01Goldan Keith A.Chief Financial OfficerOpen market sale 1,177$18.99
2026-06-01Metzger Michael AChief Executive OfficerOpen market sale 6,847$18.99
2026-02-09Metzger Michael AChief Executive OfficerOpen market sale 17,159$21.03
2026-02-09Goldan Keith A.Chief Financial OfficerOpen market sale 3,410$21.03
2026-02-06Metzger Michael AChief Executive OfficerOpen market sale 7,412$20.62
2026-02-06Goldan Keith A.Chief Financial OfficerOpen market sale 2,082$20.62
2026-02-04Metzger Michael AChief Executive OfficerGrant / award 73,000$0.00
2026-02-04Metzger Michael AChief Executive OfficerGrant / award 144,600$0.00
2026-02-04Goldan Keith A.Chief Financial OfficerGrant / award 21,500$0.00
2026-02-04Goldan Keith A.Chief Financial OfficerGrant / award 30,750$0.00
2026-02-04Jarrett JenniferReporting personGrant / award 24,000$0.00
2026-02-04Huber Martin H. Jr.Reporting personGrant / award 24,000$0.00
2026-02-04Botwood Nicholas A.J.Head of R&D, CMOGrant / award 24,000$0.00
2026-02-04Botwood Nicholas A.J.Head of R&D, CMOGrant / award 36,000$0.00
2026-02-04Podlesak DennisReporting personGrant / award 48,000$0.00
2026-02-04Rizo AleksandraReporting personGrant / award 24,000$0.00
2026-02-04Katkin KeithReporting personGrant / award 24,000$0.00
2026-02-04Legault PierreReporting personGrant / award 24,000$0.00
2026-01-30Goldan Keith A.Chief Financial OfficerOther acquisition/disposition 1,219$8.48
2025-12-01Goldan Keith A.Chief Financial OfficerGift 1,224$0.00
2025-09-08Metzger Michael AChief Executive OfficerOption exercise 157,307$10.90
2025-09-08Metzger Michael AChief Executive OfficerOpen market sale 157,307$16.41
2025-08-18Podlesak DennisReporting personOption exercise 19,200$7.20
2025-08-18Podlesak DennisReporting personOpen market sale 19,200$15.84
2025-08-15Podlesak DennisReporting personOption exercise 19,200$7.20
2025-08-15Podlesak DennisReporting personOpen market sale 19,200$15.54
2025-08-14Podlesak DennisReporting personOption exercise 19,200$7.20
2025-08-14Podlesak DennisReporting personOpen market sale 19,200$14.19
2025-07-31Goldan Keith A.Chief Financial OfficerOther acquisition/disposition 1,226$8.43
2025-07-16Goldan Keith A.Chief Financial OfficerOpen market sale 1,296$9.29
2025-07-16Metzger Michael AChief Executive OfficerOpen market sale 7,534$9.29
2025-05-19Goldan Keith A.Chief Financial OfficerOpen market purchase 3,000—
2025-05-19Huber Martin H. Jr.Reporting personOpen market purchase 5,000$8.99
2025-05-19Katkin KeithReporting personOpen market purchase 10,000$9.11
2025-05-16Botwood Nicholas A.J.Head of R&D, CMOOpen market purchase 11,765$8.99

Recent SEC filings

Official company reports and insider transaction filings. Form 4 reports a transaction; it does not by itself explain why it happened.

Source: SEC EDGAR submissions · updated 2026-10-13 14:19 UTC

FiledFormReport periodOfficial filing
2026-08-0410-Q2026-06-30 View on SEC.gov →
2026-08-048-K2026-08-04 View on SEC.gov →
2026-07-148-K2026-07-14 View on SEC.gov →
2026-07-0942026-07-08 View on SEC.gov →
2026-06-1242026-06-11 View on SEC.gov →
2026-06-108-K2026-06-10 View on SEC.gov →
2026-06-108-K2026-06-10 View on SEC.gov →
2026-06-048-K2026-06-03 View on SEC.gov →
2026-06-0242026-06-01 View on SEC.gov →
2026-06-0242026-06-01 View on SEC.gov →
2026-04-3010-Q2026-03-31 View on SEC.gov →
2026-04-308-K2026-04-30 View on SEC.gov →

Headlines about SNDX (Syndax Pharmaceuticals, Inc.). Links open the publisher — we don’t host full articles.

SEC filings ↓

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