LXRX · Lexicon Pharmaceuticals, Inc.

NASDAQ NMS - GLOBAL MARKET - Real Time Price • USD

Lexicon Pharmaceuticals Inc (LXRX)

NASDAQ NMS - GLOBAL MARKET Pharmaceuticals
Move probability → Options chain →
$1.55 -0.02 (-1.59%)
● At close: October 21 at 4:00:00 PM EDT
DAY'S RANGE $1.55
$1.55 $1.61
52-WEEK RANGE $1.55
$1.10 $2.68

What's happening

Deterministic template sentences filled in from the same sourced figures shown elsewhere on this page -- not an AI-written summary, no live model call.

Key Statistics

Market Cap$705.3M
P/E (TTM1)—
EPS2 (TTM)$-0.15
Div Yield—
Beta31.04
Volume106,894
Open1.58
Prev Close1.57
Bid / Ask1.34 / 0.00
Next Earnings 2026-11-11

Analyst Recommendations

Strong buy 3 Buy 6 Hold 3 Sell 0 Strong sell 0

Aggregate ratings for 2026-10-01 (12 analysts polled by Finnhub) — consensus count.

Performance Overview (Trailing returns vs S&P 500 benchmark)

YTD RETURN
LXRX +37.39%
vs S&P 500 +24.61%
1-YEAR RETURN
LXRX +3.95%
vs S&P 500 -10.61%
6-MONTH RETURN
LXRX -14.13%
3-MONTH RETURN
LXRX -33.61%

Valuation Measures & Ratios

Enterprise Value4$715.8M
Forward P/E5—
PEG Ratio6—
Price / Sales (TTM1)17.01
Price / Book76.11
EV4 / Revenue17.26
EV4 / EBITDA16.80
Profit Margin-147.38%
Operating Margin-141.92%
Return on Equity (ROE8)-40.40%
Return on Assets (ROA9)-26.87%
Avg Volume (3M)3,249,420
Quarterly history (5 periods)
Measure Jun '26Mar '26Sep '25Jun '25Mar '25
Market cap $1.08B — $431.0M $308.9M $167.3M
P/E -25.63 — -4.33 -2.20 -0.87
Price/Sales 16.73 — 9.36 9.21 28.89
Price/Book 6.22 — 3.59 2.39 1.36
EV/Revenue 16.89 — 9.51 10.25 35.43
EV/EBITDA -30.90 — -4.50 — —
ROE -24.26% — -82.91% -108.38% -156.00%
ROA -16.93% — -48.38% -62.19% -64.48%

Trailing-twelve-month ratios computed from SEC EDGAR quarterly figures and historical daily close prices (Alpaca). Diluted shares are derived from Net income ÷ EPS (diluted) for each quarter, not separately reported. Forward P/E/PEG unavailable (no free data source).

Glossary — what these abbreviations mean
1. TTM
Trailing twelve months — the sum of the last four reported quarters, not a calendar year or the single latest quarter.
2. EPS
Earnings per share — net income divided by diluted shares outstanding.
3. Beta
A stock's historical volatility relative to the overall market. Above 1 means it has moved more than the market; below 1, less.
4. EV (Enterprise Value)
Market cap plus total debt minus cash — roughly what it would cost to buy the whole company, debt included.
5. Forward P/E
Price divided by analysts' estimated earnings for the next 12 months, instead of trailing actual earnings.
6. PEG Ratio
P/E divided by expected earnings growth rate. A lower number can indicate a stock is cheap relative to how fast it's expected to grow.
7. Price / Book
Share price divided by book value (assets minus liabilities) per share.
8. ROE
Return on equity — net income divided by shareholders' equity, a measure of how efficiently a company turns equity into profit.
9. ROA
Return on assets — net income divided by total assets, a measure of how efficiently a company turns assets into profit.
10. MRQ
Most recent quarter — the single latest reported period, as opposed to TTM. The Financials section's "Quarterly" view below shows MRQ-style figures.
11. YoY
Year over year — percent change versus the same period one year earlier, used for growth figures like those on Compare cards and the Screener.

Short Interest

Shares Short25,828,112
Change from Prior Settlement-10.30%
% of Float—
Days to Cover (Short Ratio)6.16

Source: FINRA Rule 4560 consolidated short interest, settlement date 2026-09-30. Reported bi-monthly with a reporting lag — not real-time.

Quotes and the 1-day extended-hours chart: Yahoo Finance. Longer historical charts: Alpaca (IEX feed) — real-time but IEX-only volume (~2.5% of consolidated market volume). Fundamentals + earnings: Finnhub.

Price history

Events

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Technical signal summary

Calculating from the latest year of daily price history…

Calculating…
Show Technical Analysis Breakdown ▾ 10 Indicators

Not investment advice — read several signals together.

Indicators None active

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Starter sets
Trend
Oscillators
Volume/volatility
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History limited by data provider; markers are heuristics, not signals.

Peer and sector context

No reviewed peer group is available for this symbol.

Balanced evidence

A deterministic summary of sourced facts—not an AI verdict.

Potential strengths

Potential concerns

Rule-based facts only; absence from either side is not evidence, and this is not a recommendation.

Financials

Income statement

Line item Jun '26Mar '26Sep '25Jun '25Mar '25Sep '24Jun '24Mar '24
Revenue $692.0K $21.1M $14.2M $28.9M $1.3M $1.8M $1.6M $1.1M
Operating income -$26.5M -$996.0K -$12.2M $3.7M -$25.7M -$63.7M -$55.4M -$45.3M
Net income -$31.8M -$1.0M -$12.8M $3.3M -$25.3M -$64.8M -$53.4M -$48.4M
EPS (diluted) $-0.07 $0.00 $-0.04 $0.01 $-0.07 $-0.18 $-0.17 $-0.20
EPS (basic) $-0.07 $0.00 $-0.04 $0.01 $-0.07 $-0.18 $-0.17 $-0.20
Operating margin -$3.8K -$5 -$86 $13 -$2.0K -$3.6K -$3.4K -$4.0K

Balance sheet

Line item Jun '26Mar '26Dec '25Sep '25Jun '25Mar '25Dec '24Sep '24
Total assets $250.1M $268.8M $185.0M $205.9M $225.6M $297.7M $298.4M $321.1M
Total liabilities $75.5M $66.0M $77.4M $85.8M $96.1M $174.6M $152.5M $142.6M
Stockholders' equity $174.5M $202.9M $107.5M $120.2M $129.4M $123.0M $145.9M $178.5M
Total current assets $196.6M $186.0M $101.9M $122.5M $145.1M $245.8M $246.2M $268.6M
Total current liabilities $14.7M $9.9M $20.9M $21.7M $34.8M $110.7M $45.2M $36.0M
Cash & equivalents $40.9M $38.1M $34.3M $49.7M $21.4M $62.9M $66.7M $34.6M

Cash flow

Line item Jun '26Mar '26Dec '25Sep '25Jun '25Mar '25Dec '24Sep '24
Operating cash flow -$9.2M -$14.7M -$17.2M -$23.8M $17.0M -$43.8M -$21.5M -$53.6M
Investing cash flow -$16.5M -$70.3M $4.8M $52.1M $15.5M $40.6M $53.7M $53.5M
Financing cash flow -$512.0K $88.8M -$2.9M $0 -$45.0M -$572.0K -$104.0K -$916.0K
Free cash flow — — -$17.2M -$23.8M $17.0M — -$22.0M -$53.9M
Capital expenditures — — $0 $0 $0 — $474.0K $307.0K
Depreciation & amortization $102.0K $110.0K $118.0K $151.0K $176.0K $176.0K $125.0K $126.0K

Source: SEC EDGAR XBRL filings (10-Q/10-K), as originally tagged by the company. Quarterly cash flow is reconstructed by de-cumulating fiscal-year-to-date figures (how cash flow is tagged in 10-Qs); other quarterly lines are reported directly.

Institutional holders

SEC Form 13F filers holding LXRX as of the latest reported quarter. 13F only covers investment managers with $100M+ in assets — this is not a complete ownership picture, and does not include insiders (see Recent SEC filings below) or non-13F-eligible holders.

Institutional ownership is not available for this symbol right now.

Insider activity

Directors, officers, and 10%+ owners' reported transactions from SEC Form 4. A filing reports a transaction; it does not by itself explain why it happened.

Source: SEC EDGAR Form 4 filings · checked 25 most recent filings · covers 2026-02-23 to 2026-06-03

Recent transactions

  • Most recent: Swain Judith L (Director) — Option exercise of 89,312 shares on 2026-06-03.

Deterministic template sentences filled in from the SEC Form 4 figures in the tables below -- not an AI-written summary, no live model call.

Insider purchases & sales, last 6 months

Purchases (open market)0 sh(0 txns)
Sales (open market)0 sh(0 txns)
Net Shares+0

Counts only open-market purchases (code P) and sales (code S) — grants, option exercises, tax withholding, and gifts are excluded since they aren't a market buy/sell decision.

Insider roster

NameTitleMost Recent TransactionDateShares
Swain Judith LDirectorOption exercise2026-06-0389,312
Sullivan Diane E.DirectorOption exercise2026-06-0389,312
SOBECKI CHRISTOPHER JDirectorOption exercise2026-06-0389,312
Cheung IvanDirectorOption exercise2026-06-0389,312
BARKER SAM LDirectorOption exercise2026-06-0389,312
Amouyal PhilippeDirectorOption exercise2026-06-0389,312
DEBBANE RAYMONDDirectorOption exercise2026-06-0389,312
Artal Participations S.a r.l.Reporting personOption exercise2026-04-3020,421,735
McDermott WendySVP, Human ResourcesOption exercise2026-02-2827,697
Martens Rachel YapSVP, Partnerships & Corp StratOption exercise2026-02-2867,090
Granowitz Craig BSVP, Chief Medical OfficerOption exercise2026-02-2835,790
Gopinathan SumaSVP, DiscoveryOption exercise2026-02-2814,000
DeFrancesco LisaSVP, IR and Corp CommOption exercise2026-02-2824,674
Crum Brian TSVP, General Counsel & Secr.Option exercise2026-02-2833,457
Coiante Scott MSVP, Chief Financial OfficerOption exercise2026-02-28160,237
Exton MichaelChief Executive OfficerOption exercise2026-02-28503,263

Recent transactions

DateInsiderTitleTransactionSharesPrice
2026-06-03Swain Judith LDirectorOption exercise 89,312$0.00
2026-06-03Sullivan Diane E.DirectorOption exercise 89,312$0.00
2026-06-03SOBECKI CHRISTOPHER JDirectorOption exercise 89,312$0.00
2026-06-03Cheung IvanDirectorOption exercise 89,312$0.00
2026-06-03BARKER SAM LDirectorOption exercise 89,312$0.00
2026-06-03Amouyal PhilippeDirectorOption exercise 89,312$0.00
2026-06-03DEBBANE RAYMONDDirectorOption exercise 89,312$0.00
2026-04-30Artal Participations S.a r.l.Reporting personOption exercise 20,421,735$0.00
2026-02-28McDermott WendySVP, Human ResourcesOption exercise 27,697—
2026-02-28McDermott WendySVP, Human ResourcesOption exercise 52,316—
2026-02-28McDermott WendySVP, Human ResourcesOption exercise 144,393—
2026-02-28McDermott WendySVP, Human ResourcesTax withholding 68,107$1.47
2026-02-28Martens Rachel YapSVP, Partnerships & Corp StratOption exercise 67,090—
2026-02-28Martens Rachel YapSVP, Partnerships & Corp StratTax withholding 35,826$1.47
2026-02-28Granowitz Craig BSVP, Chief Medical OfficerOption exercise 35,790—
2026-02-28Granowitz Craig BSVP, Chief Medical OfficerOption exercise 74,226—
2026-02-28Granowitz Craig BSVP, Chief Medical OfficerOption exercise 202,260—
2026-02-28Granowitz Craig BSVP, Chief Medical OfficerTax withholding 109,098$1.47
2026-02-28Gopinathan SumaSVP, DiscoveryOption exercise 14,000—
2026-02-28Gopinathan SumaSVP, DiscoveryOption exercise 20,310—
2026-02-28Gopinathan SumaSVP, DiscoveryOption exercise 65,640—
2026-02-28Gopinathan SumaSVP, DiscoveryTax withholding 24,338$1.47
2026-02-28DeFrancesco LisaSVP, IR and Corp CommOption exercise 24,674—
2026-02-28DeFrancesco LisaSVP, IR and Corp CommOption exercise 128,190—
2026-02-28DeFrancesco LisaSVP, IR and Corp CommTax withholding 74,572$1.47
2026-02-28Crum Brian TSVP, General Counsel & Secr.Option exercise 33,457—
2026-02-28Crum Brian TSVP, General Counsel & Secr.Option exercise 69,386—
2026-02-28Crum Brian TSVP, General Counsel & Secr.Option exercise 170,163—
2026-02-28Crum Brian TSVP, General Counsel & Secr.Tax withholding 105,019$1.47
2026-02-28Coiante Scott MSVP, Chief Financial OfficerOption exercise 160,237—
2026-02-28Coiante Scott MSVP, Chief Financial OfficerTax withholding 54,881$1.47
2026-02-28Exton MichaelChief Executive OfficerOption exercise 503,263—
2026-02-28Exton MichaelChief Executive OfficerTax withholding 204,831$1.47
2026-02-25DEBBANE RAYMONDDirectorOpen market purchase 2,000$1.49
2026-02-23DEBBANE RAYMONDDirectorOpen market purchase 100,000$1.47

Recent SEC filings

Official company reports and insider transaction filings. Form 4 reports a transaction; it does not by itself explain why it happened.

Source: SEC EDGAR submissions · updated 2026-10-22 08:40 UTC

FiledFormReport periodOfficial filing
2026-08-0610-Q2026-06-30 View on SEC.gov →
2026-08-068-K2026-08-06 View on SEC.gov →
2026-06-0442026-06-03 View on SEC.gov →
2026-06-0442026-06-03 View on SEC.gov →
2026-06-0442026-06-03 View on SEC.gov →
2026-06-0442026-06-03 View on SEC.gov →
2026-06-0442026-06-03 View on SEC.gov →
2026-06-0442026-06-03 View on SEC.gov →
2026-06-0442026-06-03 View on SEC.gov →
2026-05-0842026-04-30 View on SEC.gov →
2026-05-0710-Q2026-03-31 View on SEC.gov →
2026-05-078-K2026-05-07 View on SEC.gov →

Headlines about LXRX (Lexicon Pharmaceuticals, Inc.). Links open the publisher — we don’t host full articles.

SEC filings ↓

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