TSHA · Taysha Gene Therapies, Inc.

NASDAQ NMS - GLOBAL MARKET - BOATS Real Time Price • USD

Taysha Gene Therapies Inc (TSHA)

NASDAQ NMS - GLOBAL MARKET Biotechnology
Move probability → Options chain →
$4.12 -0.00 (-0.12%)
● At close: October 21 at 4:00:00 PM EDT
$4.13 +0.01 (+0.24%)
🌙 Overnight: 11:05:38 PM EDT
DAY'S RANGE $4.12
$4.05 $4.26
52-WEEK RANGE $4.12
$3.46 $7.30

What's happening

Deterministic template sentences filled in from the same sourced figures shown elsewhere on this page -- not an AI-written summary, no live model call.

Key Statistics

Market Cap$1.36B
P/E (TTM1)—
EPS2 (TTM)$-0.41
Div Yield—
Beta31.37
Volume319,078
Open4.12
Prev Close4.12
Bid / Ask3.53 / 4.69
Next Earnings 2026-11-10

Analyst Recommendations

Strong buy 7 Buy 11 Hold 1 Sell 0 Strong sell 0

Aggregate ratings for 2026-10-01 (19 analysts polled by Finnhub) — consensus count.

Performance Overview (Trailing returns vs S&P 500 benchmark)

YTD RETURN
TSHA -25.27%
vs S&P 500 -38.05%
1-YEAR RETURN
TSHA -12.92%
vs S&P 500 -27.48%
6-MONTH RETURN
TSHA -30.92%
3-MONTH RETURN
TSHA -27.51%

Valuation Measures & Ratios

Enterprise Value4$934.8M
Forward P/E5—
PEG Ratio6-0.43
Price / Sales (TTM1)137.19
Price / Book75.62
EV4 / Revenue95.65
EV4 / EBITDA—
Profit Margin-780.33%
Operating Margin-782.50%
Return on Equity (ROE8)-56.19%
Return on Assets (ROA9)-41.84%
Avg Volume (3M)3,665,970
Quarterly history (5 periods)
Measure Jun '26Mar '26Sep '25Jun '25Mar '25
Market cap $2.44B $1.57B $1.19B $690.0M $371.4M
P/E -16.42 -12.74 -11.13 -7.27 -4.03
Price/Sales 1229.29 367.18 195.44 95.99 43.12
Price/Book 6.30 7.43 5.42 2.77 6.75
EV/Revenue 1024.79 314.10 154.87 58.19 34.51
ROE -38.39% -58.30% -48.71% -38.14% -167.17%
ROA -31.60% -41.14% -33.70% -28.46% -66.52%

Trailing-twelve-month ratios computed from SEC EDGAR quarterly figures and historical daily close prices (Alpaca). Diluted shares are derived from Net income ÷ EPS (diluted) for each quarter, not separately reported. Forward P/E/PEG unavailable (no free data source).

Glossary — what these abbreviations mean
1. TTM
Trailing twelve months — the sum of the last four reported quarters, not a calendar year or the single latest quarter.
2. EPS
Earnings per share — net income divided by diluted shares outstanding.
3. Beta
A stock's historical volatility relative to the overall market. Above 1 means it has moved more than the market; below 1, less.
4. EV (Enterprise Value)
Market cap plus total debt minus cash — roughly what it would cost to buy the whole company, debt included.
5. Forward P/E
Price divided by analysts' estimated earnings for the next 12 months, instead of trailing actual earnings.
6. PEG Ratio
P/E divided by expected earnings growth rate. A lower number can indicate a stock is cheap relative to how fast it's expected to grow.
7. Price / Book
Share price divided by book value (assets minus liabilities) per share.
8. ROE
Return on equity — net income divided by shareholders' equity, a measure of how efficiently a company turns equity into profit.
9. ROA
Return on assets — net income divided by total assets, a measure of how efficiently a company turns assets into profit.
10. MRQ
Most recent quarter — the single latest reported period, as opposed to TTM. The Financials section's "Quarterly" view below shows MRQ-style figures.
11. YoY
Year over year — percent change versus the same period one year earlier, used for growth figures like those on Compare cards and the Screener.

Short Interest

Shares Short55,020,663
Change from Prior Settlement+7.03%
% of Float—
Days to Cover (Short Ratio)11.15

Source: FINRA Rule 4560 consolidated short interest, settlement date 2026-09-30. Reported bi-monthly with a reporting lag — not real-time.

Quotes and the 1-day extended-hours chart: Yahoo Finance. Longer historical charts: Alpaca (IEX feed) — real-time but IEX-only volume (~2.5% of consolidated market volume). Fundamentals + earnings: Finnhub.

Price history

Events

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Technical signal summary

Calculating from the latest year of daily price history…

Calculating…
Show Technical Analysis Breakdown ▾ 10 Indicators

Not investment advice — read several signals together.

Indicators None active

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Starter sets
Trend
Oscillators
Volume/volatility
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History limited by data provider; markers are heuristics, not signals.

Peer and sector context

No reviewed peer group is available for this symbol.

Balanced evidence

A deterministic summary of sourced facts—not an AI verdict.

Potential strengths

  • Latest SEC filing is Form 10-Q, filed 2026-08-11; review it for current changes and risks. SEC EDGAR ↗

Potential concerns

Rule-based facts only; absence from either side is not evidence, and this is not a recommendation.

Financials

Income statement

Line item Jun '26Mar '26Sep '25Jun '25Mar '25Sep '24Jun '24Mar '24
Revenue $0 $0 $0 $2.0M $2.3M $1.8M $1.1M $3.4M
Operating income -$47.3M -$43.5M -$34.0M -$26.8M -$21.4M -$25.9M -$21.3M -$24.3M
Net income -$46.6M -$42.4M -$32.7M -$26.9M -$21.5M -$25.5M -$20.9M -$24.1M
EPS (diluted) $-0.13 $-0.12 $-0.09 $-0.09 $-0.08 $-0.10 $-0.09 $-0.10
EPS (basic) $-0.13 $-0.12 $-0.09 $-0.09 $-0.08 $-0.10 $-0.09 $-0.10
Operating margin — — — -$1.3K -$931 -$1.4K -$1.9K -$713

Balance sheet

Line item Jun '26Mar '26Dec '25Sep '25Jun '25Mar '25Dec '24Sep '24
Total assets $470.4M $300.4M $343.3M $316.6M $333.3M $138.4M $160.4M $180.2M
Total liabilities $83.2M $88.4M $96.4M $97.6M $84.6M $83.3M $88.8M $91.4M
Stockholders' equity $387.3M $211.9M $246.9M $219.0M $248.7M $55.1M $71.5M $88.8M
Total current assets $461.4M $282.2M $324.6M $300.0M $316.3M $120.7M $142.1M $161.6M
Total current liabilities $26.0M $20.1M $26.6M $28.6M $25.3M $22.6M $26.2M $29.3M
Cash & equivalents $455.4M $276.6M $319.8M $297.3M $312.8M $116.6M $139.0M $157.7M

Cash flow

Line item Jun '26Mar '26Dec '25Sep '25Jun '25Mar '25Dec '24Sep '24
Operating cash flow -$40.4M -$40.9M -$26.7M -$24.2M -$20.2M -$22.0M -$18.3M -$21.6M
Investing cash flow $1.0K -$3.0M -$247.0K -$48.0K $62.0K -$371.0K $13.0K -$35.0K
Financing cash flow $216.7M $711.0K $49.6M $8.8M $216.3M -$52.0K -$357.0K $6.6M
Free cash flow -$40.4M -$40.9M -$27.0M -$24.3M -$20.2M -$22.4M -$18.3M -$21.6M
Capital expenditures -$1.0K $24.0K $250.0K $108.0K $2.0K $378.0K -$2.0K $35.0K
Share-based compensation $5.8M $5.5M $3.5M $3.3M $3.2M $3.3M $3.2M $3.4M

Source: SEC EDGAR XBRL filings (10-Q/10-K), as originally tagged by the company. Quarterly cash flow is reconstructed by de-cumulating fiscal-year-to-date figures (how cash flow is tagged in 10-Qs); other quarterly lines are reported directly.

Institutional holders

SEC Form 13F filers holding TSHA as of the latest reported quarter. 13F only covers investment managers with $100M+ in assets — this is not a complete ownership picture, and does not include insiders (see Recent SEC filings below) or non-13F-eligible holders.

Source: Business Quant SEC Form 13F · report period 2026-06-30 · 31 filers

Held by These Filers70.3%
Shares Outstanding369,044,040
FilerSharesValue% OutQtr ChangeFiled
Avoro Capital Advisors LLC 23,888,888 $162.7M 6.47% +10.1% 2026-08-14
RA CAPITAL MANAGEMENT, L.P. 23,555,648 $160.4M 6.38% +0.0% 2026-08-14
Goldman Sachs Group Inc 22,713,118 $154.7M 6.15% +1.5% 2026-08-14
BlackRock, Inc. 20,691,927 $140.9M 5.61% +12.7% 2026-08-07
Vestal Point Capital, LP 19,415,000 $132.2M 5.26% +7.9% 2026-08-14
Morgan Stanley 16,487,479 $112.3M 4.47% -8.2% 2026-08-11
RTW INVESTMENTS, LP 13,560,258 $92.3M 3.67% -0.9% 2026-08-14
FMR LLC 13,336,413 $90.8M 3.61% -6.9% 2026-08-13
VANGUARD CAPITAL MANAGEMENT LLC 12,478,595 $85.0M 3.38% +22.0% 2026-06-30
State Street Corp 11,421,920 $77.8M 3.10% +1.9% 2026-08-07
Siren, L.L.C. 9,846,579 $67.1M 2.67% +11.5% 2026-08-13
Octagon Capital Advisors LP 9,693,244 $66.0M 2.63% +9.4% 2026-08-14
GEODE CAPITAL MANAGEMENT, LLC 6,560,394 $44.7M 1.78% +18.6% 2026-08-12
Polar Capital Holdings Plc 5,117,133 $34.8M 1.39% -9.5% 2026-08-14
MPM BioImpact LLC 4,500,000 $30.6M 1.22% +0.0% 2026-08-14
D. E. Shaw & Co., Inc. 4,398,652 $30.0M 1.19% -0.6% 2026-08-14
BAKER BROS. ADVISORS LP 4,004,756 $27.3M 1.09% +0.0% 2026-08-14
WELLINGTON MANAGEMENT GROUP LLP 3,975,605 $27.1M 1.08% +534.7% 2026-08-14
HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND 3,885,501 $26.5M 1.05% +34.8% 2026-08-13
Casdin Capital, LLC 3,250,000 $22.1M 0.88% +0.0% 2026-08-14
VANGUARD PORTFOLIO MANAGEMENT LLC 3,140,009 $21.4M 0.85% +55.3% 2026-06-30
ADAR1 Capital Management, LLC 3,040,466 $20.7M 0.82% +2.0% 2026-08-14
Pictet Asset Management Holding SA 2,770,701 $18.9M 0.75% +14242.6% 2026-07-30
Aberdeen Group plc 2,327,152 $15.8M 0.63% +127.9% 2026-07-31
FARALLON CAPITAL MANAGEMENT, L.L.C. 2,250,000 $15.3M 0.61% +0.0% 2026-08-14

Insider activity

Directors, officers, and 10%+ owners' reported transactions from SEC Form 4. A filing reports a transaction; it does not by itself explain why it happened.

Source: SEC EDGAR Form 4 filings · checked 25 most recent filings · covers 2025-01-02 to 2026-07-10

Recent transactions

  • Insiders have net sold 200,000 shares over the last 182 days, across 0 purchases and 1 sale.
  • Most recent: Nagendran Sukumar (President and Head of R&D) — Open market sale of 200,000 shares on 2026-07-10.

Deterministic template sentences filled in from the SEC Form 4 figures in the tables below -- not an AI-written summary, no live model call.

Insider purchases & sales, last 6 months

Purchases (open market)0 sh(0 txns)
Sales (open market)200,000 sh(1 txns)
Net Shares-200,000

Counts only open-market purchases (code P) and sales (code S) — grants, option exercises, tax withholding, and gifts are excluded since they aren't a market buy/sell decision.

Insider roster

NameTitleMost Recent TransactionDateShares
Nagendran SukumarPresident and Head of R&DOpen market sale2026-07-10200,000
Stalfort John A IIIReporting personGrant / award2026-06-0121,335
Donenberg Phillip B.Reporting personGrant / award2026-06-0121,335
Long Alison SReporting personGrant / award2026-06-0121,335
Sepp-Lorenzino LauraReporting personGrant / award2026-06-0121,335
Alam KamranCHIEF FINANCIAL OFFICEROpen market sale2026-02-041,655
Nolan Sean P.Chief Executive OfficerOpen market sale2026-01-2641,312
Manning Paul BReporting personOpen market purchase2025-05-30750,000

Recent transactions

DateInsiderTitleTransactionSharesPrice
2026-07-10Nagendran SukumarPresident and Head of R&DOpen market sale 200,000$6.24
2026-06-01Stalfort John A IIIReporting personGrant / award 21,335$0.00
2026-06-01Donenberg Phillip B.Reporting personGrant / award 21,335$0.00
2026-06-01Long Alison SReporting personGrant / award 21,335$0.00
2026-06-01Sepp-Lorenzino LauraReporting personGrant / award 21,335$0.00
2026-04-10Nagendran SukumarPresident and Head of R&DOption exercise 19,021$1.71
2026-04-10Nagendran SukumarPresident and Head of R&DOpen market sale 200,000$4.46
2026-02-04Alam KamranCHIEF FINANCIAL OFFICEROpen market sale 1,655$4.52
2026-01-26Nagendran SukumarPresident and Head of R&DOpen market sale 26,918$4.61
2026-01-26Nolan Sean P.Chief Executive OfficerOpen market sale 41,312$4.61
2026-01-26Alam KamranCHIEF FINANCIAL OFFICEROpen market sale 23,849$4.61
2026-01-23Nagendran SukumarPresident and Head of R&DOpen market sale 89,132$4.75
2026-01-23Nolan Sean P.Chief Executive OfficerOpen market sale 136,789$4.75
2026-01-23Alam KamranCHIEF FINANCIAL OFFICEROpen market sale 78,968$4.75
2026-01-12Alam KamranCHIEF FINANCIAL OFFICERGrant / award 359,000$0.00
2026-01-12Nolan Sean P.Chief Executive OfficerGrant / award 1,008,000$0.00
2026-01-12Nagendran SukumarPresident and Head of R&DOption exercise 111,324$0.70
2026-01-12Nagendran SukumarPresident and Head of R&DOption exercise 88,676$1.71
2026-01-12Nagendran SukumarPresident and Head of R&DOpen market sale 200,000$4.71
2026-01-12Nagendran SukumarPresident and Head of R&DGrant / award 427,000$0.00
2025-12-01Nagendran SukumarPresident and Head of R&DOption exercise 260,047$1.71
2025-12-01Nagendran SukumarPresident and Head of R&DOpen market sale 260,047$4.51
2025-11-28Nagendran SukumarPresident and Head of R&DOption exercise 70,172$0.70
2025-11-28Nagendran SukumarPresident and Head of R&DOption exercise 39,953$1.71
2025-11-28Nagendran SukumarPresident and Head of R&DOpen market sale 110,125$4.75
2025-09-10Nagendran SukumarPresident and Head of R&DOption exercise 41,150$0.70
2025-09-10Nagendran SukumarPresident and Head of R&DOpen market sale 200,000$3.23
2025-08-21Nagendran SukumarPresident and Head of R&DOpen market sale 57,054$2.85
2025-08-21Alam KamranCHIEF FINANCIAL OFFICEROpen market sale 54,491$2.85
2025-06-02Stalfort John A IIIReporting personGrant / award 56,623$0.00
2025-06-02Donenberg Phillip B.Reporting personGrant / award 56,623$0.00
2025-06-02Long Alison SReporting personGrant / award 56,623$0.00
2025-06-02Sepp-Lorenzino LauraReporting personGrant / award 56,623$0.00
2025-05-30Manning Paul BReporting personOpen market purchase 750,000$2.75
2025-03-11Alam KamranCHIEF FINANCIAL OFFICERTax withholding 29,843$1.69
2025-01-02Nolan Sean P.Chief Executive OfficerGrant / award 892,500$0.00
2025-01-02Nagendran SukumarPresident and Head of R&DGrant / award 324,500$0.00

Recent SEC filings

Official company reports and insider transaction filings. Form 4 reports a transaction; it does not by itself explain why it happened.

Source: SEC EDGAR submissions · updated 2026-10-21 23:09 UTC

FiledFormReport periodOfficial filing
2026-08-1110-Q2026-06-30 View on SEC.gov →
2026-08-118-K2026-08-11 View on SEC.gov →
2026-07-1042026-07-10 View on SEC.gov →
2026-06-258-K2026-06-24 View on SEC.gov →
2026-06-228-K2026-06-22 View on SEC.gov →
2026-06-0242026-06-01 View on SEC.gov →
2026-06-0242026-06-01 View on SEC.gov →
2026-06-0242026-06-01 View on SEC.gov →
2026-06-0242026-06-01 View on SEC.gov →
2026-06-028-K2026-06-01 View on SEC.gov →
2026-05-0610-Q2026-03-31 View on SEC.gov →
2026-05-068-K2026-05-06 View on SEC.gov →

Headlines about TSHA (Taysha Gene Therapies, Inc.). Links open the publisher — we don’t host full articles.

SEC filings ↓

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