DFTX · Definium Therapeutics, Inc. Common Shares

NASDAQ NMS - GLOBAL MARKET - BOATS Real Time Price • USD

Definium Therapeutics Inc (DFTX)

NASDAQ NMS - GLOBAL MARKET Pharmaceuticals
Move probability → Options chain →
$35.47 +0.38 (+1.07%)
● At close: October 21 at 4:00:00 PM EDT
DAY'S RANGE $35.47
$35.13 $36.31
52-WEEK RANGE $35.47
$10.46 $49.70

What's happening

Deterministic template sentences filled in from the same sourced figures shown elsewhere on this page -- not an AI-written summary, no live model call.

Key Statistics

Market Cap$4.71B
P/E (TTM1)—
EPS2 (TTM)$-3.43
Div Yield—
Beta32.25
Volume520,735
Open35.28
Prev Close35.09
Bid / Ask30.84 / 42.16
Next Earnings 2026-11-05

Analyst Recommendations

Strong buy 9 Buy 14 Hold 1 Sell 0 Strong sell 0

Aggregate ratings for 2026-10-01 (24 analysts polled by Finnhub) — consensus count.

Performance Overview (Trailing returns vs S&P 500 benchmark)

YTD RETURN
DFTX +146.23%
vs S&P 500 +133.83%
1-YEAR RETURN
DFTX +141.54%
vs S&P 500 +126.17%
6-MONTH RETURN
DFTX +48.85%
3-MONTH RETURN
DFTX -22.97%

Valuation Measures & Ratios

Enterprise Value4$4.11B
Forward P/E5—
PEG Ratio6-0.07
Price / Sales (TTM1)—
Price / Book76.38
EV4 / Revenue—
EV4 / EBITDA—
Profit Margin—
Operating Margin—
Return on Equity (ROE8)-85.23%
Return on Assets (ROA9)-64.58%
Avg Volume (3M)2,715,520
Quarterly history (5 periods)
Measure Jun '26Mar '26Sep '25Jun '25Mar '25
Market cap $5.19B $2.05B $1.02B $555.2M $390.2M
P/E -15.00 -9.75 -6.91 -6.48 -4.01
Price/Book 5.65 7.36 7.79 2.99 1.75
ROE -37.67% -75.47% -112.59% -46.19% -43.66%
ROA -31.10% -52.44% -62.06% -32.30% -35.34%

Trailing-twelve-month ratios computed from SEC EDGAR quarterly figures and historical daily close prices (Alpaca). Diluted shares are derived from Net income ÷ EPS (diluted) for each quarter, not separately reported. Forward P/E/PEG unavailable (no free data source).

Glossary — what these abbreviations mean
1. TTM
Trailing twelve months — the sum of the last four reported quarters, not a calendar year or the single latest quarter.
2. EPS
Earnings per share — net income divided by diluted shares outstanding.
3. Beta
A stock's historical volatility relative to the overall market. Above 1 means it has moved more than the market; below 1, less.
4. EV (Enterprise Value)
Market cap plus total debt minus cash — roughly what it would cost to buy the whole company, debt included.
5. Forward P/E
Price divided by analysts' estimated earnings for the next 12 months, instead of trailing actual earnings.
6. PEG Ratio
P/E divided by expected earnings growth rate. A lower number can indicate a stock is cheap relative to how fast it's expected to grow.
7. Price / Book
Share price divided by book value (assets minus liabilities) per share.
8. ROE
Return on equity — net income divided by shareholders' equity, a measure of how efficiently a company turns equity into profit.
9. ROA
Return on assets — net income divided by total assets, a measure of how efficiently a company turns assets into profit.
10. MRQ
Most recent quarter — the single latest reported period, as opposed to TTM. The Financials section's "Quarterly" view below shows MRQ-style figures.
11. YoY
Year over year — percent change versus the same period one year earlier, used for growth figures like those on Compare cards and the Screener.

Short Interest

Shares Short11,344,959
Change from Prior Settlement-3.74%
% of Float—
Days to Cover (Short Ratio)4.89

Source: FINRA Rule 4560 consolidated short interest, settlement date 2026-09-30. Reported bi-monthly with a reporting lag — not real-time.

Quotes and the 1-day extended-hours chart: Yahoo Finance. Longer historical charts: Alpaca (IEX feed) — real-time but IEX-only volume (~2.5% of consolidated market volume). Fundamentals + earnings: Finnhub.

Price history

Events

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Technical signal summary

Calculating from the latest year of daily price history…

Calculating…
Show Technical Analysis Breakdown ▾ 10 Indicators

Not investment advice — read several signals together.

Indicators None active

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Starter sets
Trend
Oscillators
Volume/volatility
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History limited by data provider; markers are heuristics, not signals.

Peer and sector context

No reviewed peer group is available for this symbol.

Balanced evidence

A deterministic summary of sourced facts—not an AI verdict.

Potential strengths

Potential concerns

  • Latest SEC filing is Form 4, filed 2026-09-29; review it for current changes and risks. SEC EDGAR ↗

Rule-based facts only; absence from either side is not evidence, and this is not a recommendation.

Financials

Income statement

Line item Jun '26Mar '26Sep '25Jun '25Mar '25Sep '24Jun '24Mar '24
Operating income -$75.1M -$59.2M -$45.7M -$40.9M -$32.2M -$24.8M -$24.5M -$22.2M
Net income -$159.0M -$77.1M -$67.3M -$42.7M -$23.3M -$13.7M -$5.9M -$54.4M
EPS (diluted) $-1.44 $-0.71 $-0.78 $-0.50 $-0.35 $-0.27 $-0.26 $-1.14
EPS (basic) $-1.44 $-0.71 $-0.78 $-0.50 $-0.27 $-0.18 $-0.08 $-1.14

Balance sheet

Line item Jun '26Mar '26Dec '25Sep '25Jun '25Mar '25Dec '24Sep '24
Total assets $1.11B $401.3M $440.1M $236.9M $265.1M $275.3M $302.2M $319.8M
Total liabilities $194.2M $122.4M $107.8M $106.3M $79.7M $52.5M $60.7M $57.6M
Stockholders' equity $918.7M $278.8M $332.3M $130.6M $185.4M $222.8M $241.4M $262.2M
Total current assets $1.09B $380.6M $419.3M $215.8M $189.1M $221.7M $281.6M $299.4M
Total current liabilities $157.2M $81.1M $66.7M $65.4M $38.0M $30.5M $38.8M $33.3M
Cash & equivalents $655.3M $262.5M $257.8M $20.0M $33.4M $82.9M $273.7M $295.3M

Cash flow

Line item Jun '26Mar '26Dec '25Sep '25Jun '25Mar '25Dec '24Sep '24
Operating cash flow -$52.8M -$42.6M -$43.0M -$29.6M -$29.6M -$29.4M -$25.4M -$17.2M
Investing cash flow -$316.7M $42.0M $35.0M $15.4M -$39.5M -$162.5M $0 $0
Financing cash flow $762.3M $5.3M $245.9M $749.0K $19.6M $1.0M $3.8M $69.4M
Deferred income taxes — — — — — — — —
Change in accounts payable -$162.0K $1.8M -$2.8M $3.9M $1.9M $258.0K -$139.0K -$534.0K
Purchases of investments $355.7M $0 $6.0M $26.6M $73.3M $162.5M $0 $0

Source: SEC EDGAR XBRL filings (10-Q/10-K), as originally tagged by the company. Quarterly cash flow is reconstructed by de-cumulating fiscal-year-to-date figures (how cash flow is tagged in 10-Qs); other quarterly lines are reported directly.

Institutional holders

SEC Form 13F filers holding DFTX as of the latest reported quarter. 13F only covers investment managers with $100M+ in assets — this is not a complete ownership picture, and does not include insiders (see Recent SEC filings below) or non-13F-eligible holders.

Source: Business Quant SEC Form 13F · report period 2026-06-30 · 31 filers

Held by These Filers79.6%
Shares Outstanding110,684,720
FilerSharesValue% OutQtr ChangeFiled
BlackRock, Inc. 11,232,834 $528.4M 10.15% +32.5% 2026-08-07
Avoro Capital Advisors LLC 7,188,888 $338.2M 6.49% +43.8% 2026-08-14
DRIEHAUS CAPITAL MANAGEMENT LLC 6,845,276 $322.0M 6.18% +15.8% 2026-08-14
Jupiter Topco LLC 5,615,645 $264.0M 5.07% +0.0% 2026-08-14
Capital World Investors 5,367,723 $252.5M 4.85% +0.0% 2026-08-07
FMR LLC 4,752,921 $223.6M 4.29% +162.6% 2026-08-13
PRICE T ROWE ASSOCIATES INC /MD/ 4,652,032 $218.8K 4.20% +6545.7% 2026-08-14
GEODE CAPITAL MANAGEMENT, LLC 3,644,813 $171.5M 3.29% +46.1% 2026-08-12
State Street Corp 3,065,390 $144.2M 2.77% +24.0% 2026-08-07
Capital International Investors 2,963,410 $139.4M 2.68% +0.0% 2026-08-07
Octagon Capital Advisors LP 2,950,000 $138.8M 2.67% +20.9% 2026-08-14
WELLINGTON MANAGEMENT GROUP LLP 2,949,734 $138.8M 2.66% +126.1% 2026-08-14
Deep Track Capital, LP 2,750,000 $129.4M 2.48% -8.3% 2026-08-14
Commodore Capital LP 2,000,000 $94.1M 1.81% +0.0% 2026-08-14
ALLIANCEBERNSTEIN L.P. 1,803,287 $34.1M 1.63% +1866.4% 2026-08-14
Goldman Sachs Group Inc 1,800,852 $84.7M 1.63% +7.5% 2026-08-14
CITADEL ADVISORS LLC 1,688,587 $79.4M 1.53% +26.6% 2026-08-14
VANGUARD PORTFOLIO MANAGEMENT LLC 1,648,426 $77.5M 1.49% +88.9% 2026-06-30
RA CAPITAL MANAGEMENT, L.P. 1,500,000 $70.6M 1.36% +0.0% 2026-08-14
VANGUARD CAPITAL MANAGEMENT LLC 1,486,454 $69.9M 1.34% +35.5% 2026-06-30
Siren, L.L.C. 1,419,493 $66.8M 1.28% +54.4% 2026-08-13
MARSHALL WACE, LLP 1,298,946 $61.1M 1.17% +8.2% 2026-08-13
Northern Trust Corp 1,169,238 $55.0M 1.06% +46.3% 2026-08-12
Ameriprise Financial Inc 1,148,363 $54.0M 1.04% +18.8% 2026-08-14
Nuveen, LLC 1,105,314 $52.0M 1.00% +58.3% 2026-08-11

Insider activity

Directors, officers, and 10%+ owners' reported transactions from SEC Form 4. A filing reports a transaction; it does not by itself explain why it happened.

Source: SEC EDGAR Form 4 filings · checked 25 most recent filings · covers 2026-06-22 to 2026-09-25

Recent transactions

  • Insiders have net sold 140,082 shares over the last 182 days, across 0 purchases and 11 sales.
  • Most recent: Karlin Daniel (Chief Medical Officer) — Open market sale of 10,853 shares on 2026-09-25.

Deterministic template sentences filled in from the SEC Form 4 figures in the tables below -- not an AI-written summary, no live model call.

Insider purchases & sales, last 6 months

Purchases (open market)0 sh(0 txns)
Sales (open market)140,082 sh(11 txns)
Net Shares-140,082

Counts only open-market purchases (code P) and sales (code S) — grants, option exercises, tax withholding, and gifts are excluded since they aren't a market buy/sell decision.

Insider roster

NameTitleMost Recent TransactionDateShares
Karlin DanielChief Medical OfficerOpen market sale2026-09-2510,853
Barrow RobertChief Executive OfficerOpen market sale2026-09-2531,550
Wiley Matthew T.Chief Commercial OfficerOpen market sale2026-09-253,097
Sullivan MarkChief Legal OfficerOpen market sale2026-09-2514,051
Roberts BrandiChief Financial OfficerOpen market sale2026-09-253,377
Vallone Carol AReporting personOption exercise2026-09-181,086
Krebs AndreasReporting personOption exercise2026-09-181,629

Recent transactions

DateInsiderTitleTransactionSharesPrice
2026-09-25Karlin DanielChief Medical OfficerOpen market sale 10,853$36.57
2026-09-25Barrow RobertChief Executive OfficerOpen market sale 31,550$36.57
2026-09-25Wiley Matthew T.Chief Commercial OfficerOpen market sale 3,097$36.57
2026-09-25Sullivan MarkChief Legal OfficerOpen market sale 14,051$36.57
2026-09-25Roberts BrandiChief Financial OfficerOpen market sale 3,377$36.57
2026-09-18Vallone Carol AReporting personOption exercise 1,086$35.52
2026-09-18Krebs AndreasReporting personOption exercise 1,629$35.52
2026-09-14Karlin DanielChief Medical OfficerGrant / award 200,000$0.00
2026-09-14Wiley Matthew T.Chief Commercial OfficerGrant / award 125,000$0.00
2026-09-14Sullivan MarkChief Legal OfficerGrant / award 125,000$0.00
2026-09-14Roberts BrandiChief Financial OfficerGrant / award 125,000$0.00
2026-09-14Barrow RobertChief Executive OfficerGrant / award 750,000$0.00
2026-09-03Barrow RobertChief Executive OfficerOpen market sale 19,023$37.94
2026-09-02Barrow RobertChief Executive OfficerGrant / award 40,000$0.00
2026-08-12Barrow RobertChief Executive OfficerGrant / award 375,000$0.00
2026-08-12Karlin DanielChief Medical OfficerGrant / award 100,000$0.00
2026-08-12Sullivan MarkChief Legal OfficerGrant / award 62,500$0.00
2026-08-12Wiley Matthew T.Chief Commercial OfficerGrant / award 62,500$0.00
2026-08-12Roberts BrandiChief Financial OfficerGrant / award 62,500$0.00
2026-06-25Sullivan MarkChief Legal OfficerOpen market sale 13,008$45.03
2026-06-25Roberts BrandiChief Financial OfficerOpen market sale 3,013$45.03
2026-06-25Barrow RobertChief Executive OfficerOpen market sale 29,208$45.03
2026-06-25Karlin DanielChief Medical OfficerOpen market sale 10,035$45.03
2026-06-25Wiley Matthew T.Chief Commercial OfficerOpen market sale 2,867$45.03
2026-06-22Wiley Matthew T.Chief Commercial OfficerGrant / award 62,500$0.00
2026-06-22Barrow RobertChief Executive OfficerGrant / award 375,000$0.00

Recent SEC filings

Official company reports and insider transaction filings. Form 4 reports a transaction; it does not by itself explain why it happened.

Source: SEC EDGAR submissions · updated 2026-10-22 01:25 UTC

FiledFormReport periodOfficial filing
2026-09-2942026-09-25 View on SEC.gov →
2026-09-2942026-09-25 View on SEC.gov →
2026-09-2942026-09-25 View on SEC.gov →
2026-09-2942026-09-25 View on SEC.gov →
2026-09-2942026-09-25 View on SEC.gov →
2026-09-1842026-09-18 View on SEC.gov →
2026-09-1842026-09-18 View on SEC.gov →
2026-09-1442026-09-14 View on SEC.gov →
2026-09-1442026-09-14 View on SEC.gov →
2026-09-1442026-09-14 View on SEC.gov →
2026-09-1442026-09-14 View on SEC.gov →
2026-09-1442026-09-14 View on SEC.gov →

Headlines about DFTX (Definium Therapeutics, Inc. Common Shares). Links open the publisher — we don’t host full articles.

SEC filings ↓

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