CAI · Caris Life Sciences, Inc.

NASDAQ NMS - GLOBAL MARKET - Real Time Price • USD

Caris Life Sciences Inc (CAI)

NASDAQ NMS - GLOBAL MARKET Biotechnology
Move probability → Options chain →
$32.34 +1.21 (+3.89%)
● At close: October 21 at 4:00:00 PM EDT
$32.09 -0.26 (-0.79%)
🌆 After-Hours: 5:39:00 PM EDT
DAY'S RANGE $32.34
$30.98 $32.71
52-WEEK RANGE $32.34
$14.19 $33.13

What's happening

Deterministic template sentences filled in from the same sourced figures shown elsewhere on this page -- not an AI-written summary, no live model call.

Key Statistics

Market Cap$9.24B
P/E (TTM1)83.62
EPS2 (TTM)$0.37
Div Yield—
Beta30.40
Volume163,902
Open30.98
Prev Close31.14
Bid / Ask30.57 / 34.04
Next Earnings 2026-11-04

Analyst Recommendations

Strong buy 6 Buy 6 Hold 4 Sell 0 Strong sell 0

Aggregate ratings for 2026-10-01 (16 analysts polled by Finnhub) — consensus count.

Performance Overview (Trailing returns vs S&P 500 benchmark)

YTD RETURN
CAI +15.31%
vs S&P 500 +2.53%
1-YEAR RETURN
CAI -1.24%
vs S&P 500 -15.80%
6-MONTH RETURN
CAI +52.50%
3-MONTH RETURN
CAI +97.78%

Valuation Measures & Ratios

Enterprise Value4$8.49B
Forward P/E599.47
PEG Ratio6—
Price / Sales (TTM1)8.88
Price / Book78.51
EV4 / Revenue8.58
EV4 / EBITDA57.85
Profit Margin10.62%
Operating Margin12.74%
Return on Equity (ROE8)18.77%
Return on Assets (ROA9)9.34%
Avg Volume (3M)4,461,300
Quarterly history (4 periods)
Measure Jun '26Mar '26Sep '25Jun '25
Market cap — — $9.17B $241.0M
P/E — — -42.12 -0.78
Price/Sales — — 14.78 0.48
Price/Book — — 19.18 0.53
EV/Revenue — — 14.17 -0.21
EV/EBITDA — — -116.83 —
ROE — — -45.52% -68.07%
ROA — — -22.12% -32.28%

Trailing-twelve-month ratios computed from SEC EDGAR quarterly figures and historical daily close prices (Alpaca). Diluted shares are derived from Net income ÷ EPS (diluted) for each quarter, not separately reported. Forward P/E/PEG unavailable (no free data source).

Glossary — what these abbreviations mean
1. TTM
Trailing twelve months — the sum of the last four reported quarters, not a calendar year or the single latest quarter.
2. EPS
Earnings per share — net income divided by diluted shares outstanding.
3. Beta
A stock's historical volatility relative to the overall market. Above 1 means it has moved more than the market; below 1, less.
4. EV (Enterprise Value)
Market cap plus total debt minus cash — roughly what it would cost to buy the whole company, debt included.
5. Forward P/E
Price divided by analysts' estimated earnings for the next 12 months, instead of trailing actual earnings.
6. PEG Ratio
P/E divided by expected earnings growth rate. A lower number can indicate a stock is cheap relative to how fast it's expected to grow.
7. Price / Book
Share price divided by book value (assets minus liabilities) per share.
8. ROE
Return on equity — net income divided by shareholders' equity, a measure of how efficiently a company turns equity into profit.
9. ROA
Return on assets — net income divided by total assets, a measure of how efficiently a company turns assets into profit.
10. MRQ
Most recent quarter — the single latest reported period, as opposed to TTM. The Financials section's "Quarterly" view below shows MRQ-style figures.
11. YoY
Year over year — percent change versus the same period one year earlier, used for growth figures like those on Compare cards and the Screener.

Short Interest

Shares Short13,891,975
Change from Prior Settlement+4.20%
% of Float—
Days to Cover (Short Ratio)2.48

Source: FINRA Rule 4560 consolidated short interest, settlement date 2026-09-30. Reported bi-monthly with a reporting lag — not real-time.

Quotes and the 1-day extended-hours chart: Yahoo Finance. Longer historical charts: Alpaca (IEX feed) — real-time but IEX-only volume (~2.5% of consolidated market volume). Fundamentals + earnings: Finnhub.

Price history

Events

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Technical signal summary

Calculating from the latest year of daily price history…

Calculating…
Show Technical Analysis Breakdown ▾ 10 Indicators

Not investment advice — read several signals together.

Indicators None active

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Starter sets
Trend
Oscillators
Volume/volatility
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History limited by data provider; markers are heuristics, not signals.

Peer and sector context

No reviewed peer group is available for this symbol.

Balanced evidence

A deterministic summary of sourced facts—not an AI verdict.

Potential strengths

Potential concerns

Rule-based facts only; absence from either side is not evidence, and this is not a recommendation.

Financials

Income statement

Line item Jun '26Mar '26Sep '25Jun '25Mar '25Sep '24Jun '24
Revenue $263.7M $216.2M $216.8M $181.4M $120.9M $101.6M $100.0M
Operating income $26.9M $5.3M $32.6M -$18.0M -$58.0M -$60.8M -$67.0M
Net income -$637.0K -$510.0K $24.3M -$71.8M -$102.6M -$67.7M -$66.2M
EPS (diluted) $0.00 $0.00 $0.08 $-7.97 $-3.57 $-2.59 $-2.54
EPS (basic) $0.00 $0.00 $0.09 $-7.97 $-3.57 $-2.59 $-2.54
Operating margin $10 $2 $15 -$10 -$48 -$60 -$67

Balance sheet

Line item Jun '26Mar '26Dec '25Sep '25Jun '25Mar '25Dec '24Sep '24
Total assets $1.23B $1.16B $1.13B $984.6M $955.1M — $343.7M —
Total liabilities $637.9M $568.9M $548.4M $506.2M $502.2M — $620.9M —
Stockholders' equity $591.7M $593.5M $577.3M $478.4M $452.9M -$2.60B -$2.50B -$2.44B
Total current assets $1.06B $1.01B $997.8M $854.2M $833.3M — $215.7M —
Total current liabilities $191.4M $143.9M $127.1M $86.0M $90.2M — $165.4M —
Cash & equivalents — $819.9M $796.3M $753.2M $718.9M $31.2M $64.0M —

Cash flow

Line item Jun '26Mar '26Dec '25Sep '25Jun '25Mar '25Dec '24Sep '24
Operating cash flow $28.5M $32.9M $44.8M $62.4M $7.3M -$31.3M -$38.9M -$69.4M
Investing cash flow -$122.2M -$10.3M -$5.1M -$7.1M -$1.4M -$2.7M -$2.3M -$1.8M
Financing cash flow -$36.9M $824.0K $3.4M -$21.1M $681.4M $1.3M $226.0K $87.0K
Free cash flow — $22.5M $39.7M $55.3M $5.9M -$34.0M -$41.2M -$71.3M
Capital expenditures — $10.3M $5.1M $7.1M $1.4M $2.7M $2.3M $1.8M
Depreciation & amortization $6.5M $5.1M $15.6M $4.9M $6.4M $7.0M $48.9M $10.5M

Source: SEC EDGAR XBRL filings (10-Q/10-K), as originally tagged by the company. Quarterly cash flow is reconstructed by de-cumulating fiscal-year-to-date figures (how cash flow is tagged in 10-Qs); other quarterly lines are reported directly.

Institutional holders

SEC Form 13F filers holding CAI as of the latest reported quarter. 13F only covers investment managers with $100M+ in assets — this is not a complete ownership picture, and does not include insiders (see Recent SEC filings below) or non-13F-eligible holders.

Source: Business Quant SEC Form 13F · report period 2026-06-30 · 30 filers

Held by These Filers45.8%
Shares Outstanding282,888,610
FilerSharesValue% OutQtr ChangeFiled
FMR LLC 30,923,878 $551.1M 10.93% +0.4% 2026-08-13
J. H. Whitney Equity Partners VI, LLC 11,256,615 $200.6M 3.98% -38.3% 2026-08-12
COATUE MANAGEMENT LLC 9,819,992 $175.0M 3.47% +0.0% 2026-08-14
BRAIDWELL LP 8,256,032 $147.1M 2.92% +3.1% 2026-08-14
PointState Capital LP 6,828,835 $121.7M 2.41% -7.2% 2026-08-14
Jpmorgan Chase & Co 6,558,514 $120.2M 2.32% +89.5% 2026-08-12
BlackRock, Inc. 5,536,798 $98.7M 1.96% +14.0% 2026-08-07
T. Rowe Price Investment Management, Inc. 5,079,141 $90.5K 1.80% -9.1% 2026-08-14
VANGUARD PORTFOLIO MANAGEMENT LLC 4,844,431 $86.3M 1.71% +28.9% 2026-06-30
VANGUARD CAPITAL MANAGEMENT LLC 4,280,238 $76.3M 1.51% +28.6% 2026-06-30
LOS ANGELES CAPITAL MANAGEMENT LLC 3,958,531 $70.5M 1.40% +72.9% 2026-08-13
Neuberger Berman Group LLC 3,590,963 $64.0M 1.27% +0.0% 2026-08-13
ORBIMED ADVISORS LLC 2,806,811 $50.0M 0.99% +0.0% 2026-08-14
BNP PARIBAS FINANCIAL MARKETS 2,370,268 $42.2M 0.84% +46.8% 2026-08-10
MILLENNIUM MANAGEMENT LLC 2,202,647 $39.3M 0.78% +44.2% 2026-08-14
MAK CAPITAL ONE LLC 1,937,229 $34.5M 0.68% +0.0% 2026-08-14
Morgan Stanley 1,935,531 $34.5M 0.68% +79.3% 2026-08-11
Duquesne Family Office LLC 1,894,450 $33.8K 0.67% +0.0% 2026-08-14
Clearbridge Investments, LLC 1,595,877 $28.4M 0.56% +2.8% 2026-08-10
FIL Ltd 1,548,918 $27.6M 0.55% +0.2% 2026-08-13
UBS Group AG 1,423,371 $25.4M 0.50% -48.2% 2026-08-13
HRT FINANCIAL LP 1,418,392 $25.3K 0.50% +0.0% 2026-08-14
CANADA PENSION PLAN INVESTMENT BOARD 1,374,952 $24.5M 0.49% +3.9% 2026-08-14
Amundi 1,218,364 $21.7M 0.43% +5709.5% 2026-08-11
State Street Corp 1,217,548 $21.7M 0.43% +23.6% 2026-08-07

Insider activity

Directors, officers, and 10%+ owners' reported transactions from SEC Form 4. A filing reports a transaction; it does not by itself explain why it happened.

Source: SEC EDGAR Form 4 filings · checked 25 most recent filings · covers 2026-03-06 to 2026-09-22

Recent transactions

  • Insiders have net sold 905,662 shares over the last 182 days, across 2 purchases and 5 sales.
  • Most recent: Denton John Russel (See Remarks) — Open market sale of 7,500 shares on 2026-09-22.

Deterministic template sentences filled in from the SEC Form 4 figures in the tables below -- not an AI-written summary, no live model call.

Insider purchases & sales, last 6 months

Purchases (open market)99,050 sh(2 txns)
Sales (open market)1,004,712 sh(5 txns)
Net Shares-905,662

Counts only open-market purchases (code P) and sales (code S) — grants, option exercises, tax withholding, and gifts are excluded since they aren't a market buy/sell decision.

Insider roster

NameTitleMost Recent TransactionDateShares
Denton John RusselSee RemarksOpen market sale2026-09-227,500
Brille Brian JSee RemarksOption exercise2026-09-17400,000
Spetzler David BaxleyPresidentOption exercise2026-09-04250,000
CASTLEMAN PETER MDirectorGrant / award2026-08-1413,192
PHILLIPS T DANNYDirectorGrant / award2026-08-1413,192
Minor LloydDirectorGrant / award2026-08-1413,192
Gilliam Joseph EDirectorGrant / award2026-08-1413,192
Fredrickson David PaulDirectorGrant / award2026-08-1413,192
Vacirca Jeff LDirectorGrant / award2026-08-1413,192
JOHANSEN LAURA IDirectorGrant / award2026-08-1413,192
HALBERT JONDirectorGrant / award2026-08-1413,192
POSTE GEORGEDirectorGrant / award2026-05-291,600
Knowles Jonathan Kenneth CharlesDirectorGrant / award2026-05-291,600
Power Luke ThomasSee RemarksTax withholding2026-05-159,771
HALBERT DAVID DSee RemarksTax withholding2026-05-1540,712

Recent transactions

DateInsiderTitleTransactionSharesPrice
2026-09-22Denton John RusselSee RemarksOpen market sale 7,500$31.82
2026-09-17Brille Brian JSee RemarksOption exercise 400,000$2.44
2026-09-17Brille Brian JSee RemarksOpen market sale 400,000$30.33
2026-09-04Spetzler David BaxleyPresidentOption exercise 250,000$2.44
2026-09-04Spetzler David BaxleyPresidentOpen market sale 119,212$24.76
2026-09-03Spetzler David BaxleyPresidentOption exercise 1,000,000$2.44
2026-09-03Spetzler David BaxleyPresidentOpen market sale 393,100$24.76
2026-09-03Spetzler David BaxleyPresidentOpen market sale 84,900$25.32
2026-08-14CASTLEMAN PETER MDirectorGrant / award 13,192$0.00
2026-08-14PHILLIPS T DANNYDirectorGrant / award 13,192$0.00
2026-08-14Minor LloydDirectorGrant / award 13,192$0.00
2026-08-14Gilliam Joseph EDirectorGrant / award 13,192$0.00
2026-08-14Fredrickson David PaulDirectorGrant / award 13,192$0.00
2026-08-14Vacirca Jeff LDirectorGrant / award 13,192$0.00
2026-08-14JOHANSEN LAURA IDirectorGrant / award 13,192$0.00
2026-08-14HALBERT JONDirectorGrant / award 13,192$0.00
2026-05-29POSTE GEORGEDirectorGrant / award 1,600$15.62
2026-05-29Knowles Jonathan Kenneth CharlesDirectorGrant / award 1,600$15.62
2026-05-15HALBERT JONDirectorOpen market purchase 68,000$14.56
2026-05-15Denton John RusselSee RemarksTax withholding 6,047$15.25
2026-05-15Power Luke ThomasSee RemarksTax withholding 9,771$15.25
2026-05-15Spetzler David BaxleyPresidentTax withholding 13,856$15.25
2026-05-15Brille Brian JSee RemarksTax withholding 13,987$15.25
2026-05-15HALBERT DAVID DSee RemarksTax withholding 40,712$15.25
2026-05-11Vacirca Jeff LDirectorOpen market purchase 31,050$16.15
2026-03-06Power Luke ThomasSee RemarksGrant / award 63,971$0.00
2026-03-06Denton John RusselSee RemarksGrant / award 63,971$0.00
2026-03-06Spetzler David BaxleyPresidentGrant / award 83,162$0.00
2026-03-06Brille Brian JSee RemarksGrant / award 83,162$0.00
2026-03-06HALBERT DAVID DSee RemarksGrant / award 320,112$0.00

Recent SEC filings

Official company reports and insider transaction filings. Form 4 reports a transaction; it does not by itself explain why it happened.

Source: SEC EDGAR submissions · updated 2026-10-21 23:40 UTC

FiledFormReport periodOfficial filing
2026-09-2342026-09-22 View on SEC.gov →
2026-09-1742026-09-17 View on SEC.gov →
2026-09-148-K2026-09-14 View on SEC.gov →
2026-09-0442026-09-03 View on SEC.gov →
2026-08-1442026-08-14 View on SEC.gov →
2026-08-1442026-08-14 View on SEC.gov →
2026-08-1442026-08-14 View on SEC.gov →
2026-08-1442026-08-14 View on SEC.gov →
2026-08-1442026-08-14 View on SEC.gov →
2026-08-1442026-08-14 View on SEC.gov →
2026-08-1442026-08-14 View on SEC.gov →
2026-08-1442026-08-14 View on SEC.gov →

Headlines about CAI (Caris Life Sciences, Inc.). Links open the publisher — we don’t host full articles.

SEC filings ↓

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