MLYS · Mineralys Therapeutics, Inc.

NASDAQ NMS - GLOBAL MARKET - Real Time Price • USD

Mineralys Therapeutics, Inc. (MLYS)

NASDAQ NMS - GLOBAL MARKET Biotechnology
Move probability → Options chain →
$15.90 -2.27 (-12.49%)
● Market open
DAY'S RANGE $15.90
$15.72 $18.29
52-WEEK RANGE $15.90
$18.11 $47.65

What's happening

Deterministic template sentences filled in from the same sourced figures shown elsewhere on this page -- not an AI-written summary, no live model call.

Key Statistics

Market Cap$1.61B
P/E (TTM1)—
EPS2 (TTM)$-4.24
Div Yield—
Beta30.76
Volume128,354
Open18.22
Prev Close18.17
Bid / Ask15.90 / 15.93
Next Earnings 2026-11-04 (after market close)

Analyst Recommendations

Strong buy 5 Buy 9 Hold 3 Sell 0 Strong sell 0

Aggregate ratings for 2026-11-01 (17 analysts polled by Finnhub) — consensus count.

Performance Overview (Trailing returns vs S&P 500 benchmark)

YTD RETURN
MLYS -49.90%
vs S&P 500 -60.73%
1-YEAR RETURN
MLYS -55.79%
vs S&P 500 -66.95%
6-MONTH RETURN
MLYS -29.78%
3-MONTH RETURN
MLYS -28.76%

Valuation Measures & Ratios

Enterprise Value4$1.57B
Forward P/E5—
PEG Ratio6-0.26
Price / Sales (TTM1)—
Price / Book74.32
EV4 / Revenue—
EV4 / EBITDA—
Profit Margin—
Operating Margin—
Return on Equity (ROE8)-57.97%
Return on Assets (ROA9)-54.15%
Avg Volume (3M)1,209,770
Quarterly history (5 periods)
Measure Jun '26Mar '26Sep '25Jun '25Mar '25
Market cap $2.28B $2.27B $2.70B $888.4M $849.6M
P/E -6.34 -14.01 -15.09 -4.86 -4.97
Price/Book 4.15 3.55 4.68 2.83 2.49
EV/EBITDA -5.66 -12.13 -12.89 — —
ROE -65.46% -25.35% -31.01% -58.31% -50.09%
ROA -54.00% -24.78% -29.80% -54.46% -48.20%

Trailing-twelve-month ratios computed from SEC EDGAR quarterly figures and historical daily close prices (Alpaca). Diluted shares are derived from Net income ÷ EPS (diluted) for each quarter, not separately reported. Forward P/E/PEG unavailable (no free data source).

Glossary — what these abbreviations mean
1. TTM
Trailing twelve months — the sum of the last four reported quarters, not a calendar year or the single latest quarter.
2. EPS
Earnings per share — net income divided by diluted shares outstanding.
3. Beta
A stock's historical volatility relative to the overall market. Above 1 means it has moved more than the market; below 1, less.
4. EV (Enterprise Value)
Market cap plus total debt minus cash — roughly what it would cost to buy the whole company, debt included.
5. Forward P/E
Price divided by analysts' estimated earnings for the next 12 months, instead of trailing actual earnings.
6. PEG Ratio
P/E divided by expected earnings growth rate. A lower number can indicate a stock is cheap relative to how fast it's expected to grow.
7. Price / Book
Share price divided by book value (assets minus liabilities) per share.
8. ROE
Return on equity — net income divided by shareholders' equity, a measure of how efficiently a company turns equity into profit.
9. ROA
Return on assets — net income divided by total assets, a measure of how efficiently a company turns assets into profit.
10. MRQ
Most recent quarter — the single latest reported period, as opposed to TTM. The Financials section's "Quarterly" view below shows MRQ-style figures.
11. YoY
Year over year — percent change versus the same period one year earlier, used for growth figures like those on Compare cards and the Screener.

Short Interest

Shares Short7,438,452
Change from Prior Settlement-4.70%
% of Float—
Days to Cover (Short Ratio)5.33

Source: FINRA Rule 4560 consolidated short interest, settlement date 2026-10-15. Reported bi-monthly with a reporting lag — not real-time.

Quotes and the 1-day extended-hours chart: Yahoo Finance. Longer historical charts: Alpaca (IEX feed) — real-time but IEX-only volume (~2.5% of consolidated market volume). Fundamentals + earnings: Finnhub.

Price history

Events

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Technical signal summary

Calculating from the latest year of daily price history…

Calculating…
Show Technical Analysis Breakdown ▾ 10 Indicators

Not investment advice — read several signals together.

Indicators None active

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Starter sets
Trend
Oscillators
Volume/volatility
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History limited by data provider; markers are heuristics, not signals.

Peer and sector context

No reviewed peer group is available for this symbol.

Balanced evidence

A deterministic summary of sourced facts—not an AI verdict.

Potential strengths

  • Latest SEC filing is Form 8-K, filed 2026-10-29; review it for current changes and risks. SEC EDGAR ↗

Potential concerns

Rule-based facts only; absence from either side is not evidence, and this is not a recommendation.

Financials

Income statement

Line item Jun '26Mar '26Sep '25Jun '25Mar '25Sep '24Jun '24Mar '24
Operating income -$246.0M -$45.3M -$41.1M -$46.7M -$44.4M -$60.1M -$45.2M -$35.4M
Net income -$241.1M -$39.3M -$36.9M -$43.3M -$42.2M -$56.3M -$41.0M -$31.5M
EPS (diluted) $-2.85 $-0.47 $-0.52 $-0.66 $-0.79 $-1.13 $-0.83 $-0.70
EPS (basic) $-2.85 $-0.47 $-0.52 $-0.66 $-0.79 $-1.13 $-0.83 $-0.70

Balance sheet

Line item Jun '26Mar '26Dec '25Sep '25Jun '25Mar '25Dec '24Sep '24
Total assets $667.9M $652.9M $661.8M $599.9M $335.7M $354.9M $205.9M $268.3M
Total liabilities $116.9M — $15.1M — — — — —
Stockholders' equity $550.9M $638.1M $646.7M $576.4M $313.6M $341.6M $191.3M $236.9M
Total current assets $665.8M $652.5M $661.4M $599.8M $335.3M $354.5M $205.4M $267.7M
Total current liabilities $19.3M $14.7M $15.1M $23.5M $22.2M $13.4M $14.6M $31.3M
Cash & equivalents $138.3M $112.8M $172.9M $217.6M $101.8M $165.0M $114.1M $97.3M

Cash flow

Line item Jun '26Mar '26Dec '25Sep '25Jun '25Mar '25Dec '24Sep '24
Operating cash flow -$32.6M -$39.5M -$37.9M -$28.9M -$30.2M -$45.5M -$66.8M -$50.2M
Investing cash flow -$185.2M -$44.9M -$103.5M -$150.5M -$42.9M -$92.9M $83.6M $79.6M
Financing cash flow $243.3M $24.3M $96.7M $295.2M $9.8M $189.3M $90.0K -$1.0K
Depreciation & amortization $5.0K $6.0K $13.0K $15.0K $16.0K $15.0K $15.0K $11.0K
Share-based compensation $7.4M $6.5M $5.3M $5.8M $4.6M $3.6M $3.1M $3.1M
Deferred income taxes — — $0 — — — $0 —

Source: SEC EDGAR XBRL filings (10-Q/10-K), as originally tagged by the company. Quarterly cash flow is reconstructed by de-cumulating fiscal-year-to-date figures (how cash flow is tagged in 10-Qs); other quarterly lines are reported directly.

Institutional holders

SEC Form 13F filers holding MLYS as of the latest reported quarter. 13F only covers investment managers with $100M+ in assets — this is not a complete ownership picture, and does not include insiders (see Recent SEC filings below) or non-13F-eligible holders.

Source: Business Quant SEC Form 13F · report period 2026-06-30 · 30 filers

Held by These Filers90.0%
Shares Outstanding84,727,282
FilerSharesValue% OutQtr ChangeFiled
Catalys Pacific, LLC 7,903,838 $213.2M 9.33% +0.0% 2026-08-05
RA CAPITAL MANAGEMENT, L.P. 7,692,750 $207.6M 9.08% +0.0% 2026-08-14
BlackRock, Inc. 5,887,038 $158.8M 6.95% +31.4% 2026-08-07
Samsara BioCapital, LLC 5,871,018 $158.4M 6.93% +0.0% 2026-08-14
FMR LLC 4,511,689 $121.7M 5.32% -7.2% 2026-08-13
State Street Corp 4,141,636 $111.7M 4.89% +41.1% 2026-08-07
DEERFIELD MANAGEMENT COMPANY, L.P. 3,958,000 $106.8M 4.67% +0.0% 2026-08-14
VANGUARD CAPITAL MANAGEMENT LLC 2,756,770 $74.4M 3.25% +12.3% 2026-06-30
Laurion Capital Management LP 2,506,152 $67.6M 2.96% +12.3% 2026-08-07
PRICE T ROWE ASSOCIATES INC /MD/ 2,262,476 $61.0K 2.67% +68.4% 2026-08-14
ORBIMED ADVISORS LLC 2,110,300 $56.9M 2.49% +2.8% 2026-08-14
Capital World Investors 1,997,607 $53.9M 2.36% +401.7% 2026-08-07
ARMISTICE CAPITAL, LLC 1,736,000 $46.8M 2.05% +47.6% 2026-08-14
Troluce Capital Advisors LLC 1,728,753 $46.6M 2.04% +163.9% 2026-08-14
Franklin Resources Inc 1,635,520 $44.1M 1.93% -8.4% 2026-08-04
Andera Partners 1,591,917 $42.9M 1.88% +0.0% 2026-07-22
GEODE CAPITAL MANAGEMENT, LLC 1,584,326 $42.8M 1.87% +21.8% 2026-08-12
SR ONE CAPITAL MANAGEMENT, LP 1,563,966 $42.2M 1.85% +0.0% 2026-08-12
Bank Of America Corp /De/ 1,505,547 $40.6M 1.78% +36.8% 2026-08-14
SPHERA FUNDS MANAGEMENT LTD. 1,469,971 $39.7M 1.73% +9.7% 2026-08-14
Goldman Sachs Group Inc 1,458,676 $39.4M 1.72% +85.8% 2026-08-14
Pictet Asset Management Holding SA 1,430,649 $38.6M 1.69% +38.3% 2026-07-30
Polar Capital Holdings Plc 1,420,854 $38.3M 1.68% -5.3% 2026-08-14
MILLENNIUM MANAGEMENT LLC 1,221,758 $33.0M 1.44% +132.6% 2026-08-14
Ghisallo Capital Management LLC 1,125,000 $30.4M 1.33% +0.0% 2026-08-14

Insider activity

Directors, officers, and 10%+ owners' reported transactions from SEC Form 4. A filing reports a transaction; it does not by itself explain why it happened.

Source: SEC EDGAR Form 4 filings · checked 25 most recent filings · covers 2026-04-09 to 2026-10-19

Recent transactions

  • Insiders have net sold 468,606 shares over the last 182 days, across 0 purchases and 24 sales.
  • Most recent: Peterson Kristine (Director) — Grant / award of 12,400 shares on 2026-10-19.

Deterministic template sentences filled in from the SEC Form 4 figures in the tables below -- not an AI-written summary, no live model call.

Insider purchases & sales, last 6 months

Purchases (open market)0 sh(0 txns)
Sales (open market)468,606 sh(24 txns)
Net Shares-468,606

Counts only open-market purchases (code P) and sales (code S) — grants, option exercises, tax withholding, and gifts are excluded since they aren't a market buy/sell decision.

Insider roster

NameTitleMost Recent TransactionDateShares
Peterson KristineDirectorGrant / award2026-10-1912,400
COATS LONNELDirectorGrant / award2026-10-1912,400
Congleton JonChief Executive OfficerOpen market sale2026-09-3075,000
Slingsby Brian TaylorDirectorOpen market sale2026-09-22104,320
Warren EricChief Commercial OfficerOption exercise2026-09-217,438
Karydas DaphneDirectorOption exercise2026-09-153,000
Ferguson James J. IIIChief Medical OfficerGrant / award2026-08-10102,400
Rodman David MalcomChief Medical OfficerOption exercise2026-08-102,170

Recent transactions

DateInsiderTitleTransactionSharesPrice
2026-10-19Peterson KristineDirectorGrant / award 12,400$0.00
2026-10-19COATS LONNELDirectorGrant / award 12,400$0.00
2026-09-30Congleton JonChief Executive OfficerOpen market sale 75,000$25.46
2026-09-22Slingsby Brian TaylorDirectorOpen market sale 104,320$28.81
2026-09-21Warren EricChief Commercial OfficerOption exercise 7,438$13.24
2026-09-21Warren EricChief Commercial OfficerOpen market sale 7,438$28.12
2026-09-15Karydas DaphneDirectorOption exercise 3,000$12.02
2026-09-15Karydas DaphneDirectorOpen market sale 3,000$28.58
2026-08-21Warren EricChief Commercial OfficerOption exercise 7,437$13.24
2026-08-21Warren EricChief Commercial OfficerOpen market sale 7,437$25.98
2026-08-10Ferguson James J. IIIChief Medical OfficerGrant / award 102,400$0.00
2026-08-10Rodman David MalcomChief Medical OfficerOption exercise 2,170$16.00
2026-08-10Rodman David MalcomChief Medical OfficerOpen market sale 2,170$27.09
2026-07-21Warren EricChief Commercial OfficerOption exercise 7,438$13.24
2026-07-21Warren EricChief Commercial OfficerOpen market sale 7,438$26.87
2026-07-17Rodman David MalcomChief Medical OfficerOption exercise 416$15.44
2026-07-17Rodman David MalcomChief Medical OfficerOpen market sale 416$26.53
2026-07-15Rodman David MalcomChief Medical OfficerOpen market sale 6,349$26.61
2026-07-13Congleton JonChief Executive OfficerOpen market sale 10,700$27.24
2026-07-13Rodman David MalcomChief Medical OfficerOption exercise 3,542$10.20
2026-07-13Rodman David MalcomChief Medical OfficerOption exercise 4,167$14.25
2026-07-13Rodman David MalcomChief Medical OfficerOption exercise 6,349$1.08
2026-07-13Rodman David MalcomChief Medical OfficerOpen market sale 14,058$27.58
2026-07-09Rodman David MalcomChief Medical OfficerOption exercise 2,171$16.00
2026-07-09Rodman David MalcomChief Medical OfficerOpen market sale 2,171$30.30
2026-06-30Congleton JonChief Executive OfficerOpen market sale 58,000$25.94
2026-06-30Congleton JonChief Executive OfficerOpen market sale 17,000$26.82
2026-06-26Warren EricChief Commercial OfficerOption exercise 104,124$13.24
2026-06-26Warren EricChief Commercial OfficerOpen market sale 104,124$25.90
2026-06-17Rodman David MalcomChief Medical OfficerOption exercise 4,167$14.25
2026-06-17Rodman David MalcomChief Medical OfficerOption exercise 417$15.44
2026-06-17Rodman David MalcomChief Medical OfficerOpen market sale 4,584$25.00
2026-06-17Karydas DaphneDirectorOption exercise 3,000$12.02
2026-06-17Karydas DaphneDirectorOpen market sale 3,000$25.00
2026-06-15Rodman David MalcomChief Medical OfficerOption exercise 3,542$10.20
2026-06-15Rodman David MalcomChief Medical OfficerOpen market sale 9,890$23.81
2026-06-12Rodman David MalcomChief Medical OfficerOption exercise 6,349$1.08
2026-06-12Rodman David MalcomChief Medical OfficerOpen market sale 6,349$23.93
2026-06-10Rodman David MalcomChief Medical OfficerOption exercise 2,170$16.00
2026-06-10Rodman David MalcomChief Medical OfficerOpen market sale 2,170$25.00
2026-05-18Rodman David MalcomChief Medical OfficerOption exercise 417$15.44
2026-05-18Rodman David MalcomChief Medical OfficerOpen market sale 417$27.55
2026-05-13Rodman David MalcomChief Medical OfficerOption exercise 3,541$10.20
2026-05-13Rodman David MalcomChief Medical OfficerOption exercise 4,166$14.25
2026-05-13Rodman David MalcomChief Medical OfficerOpen market sale 14,056$28.58
2026-05-12Rodman David MalcomChief Medical OfficerOption exercise 6,348$1.08
2026-05-12Rodman David MalcomChief Medical OfficerOpen market sale 6,348$29.36
2026-05-11Rodman David MalcomChief Medical OfficerOption exercise 2,171$16.00
2026-05-11Rodman David MalcomChief Medical OfficerOpen market sale 2,171$29.71
2026-04-17Rodman David MalcomChief Medical OfficerOption exercise 416$15.44
2026-04-17Rodman David MalcomChief Medical OfficerOpen market sale 416$31.33
2026-04-15Rodman David MalcomChief Medical OfficerOpen market sale 6,348$27.66
2026-04-13Rodman David MalcomChief Medical OfficerOption exercise 6,349$1.08
2026-04-13Rodman David MalcomChief Medical OfficerOption exercise 3,542$10.20
2026-04-13Rodman David MalcomChief Medical OfficerOption exercise 4,167$14.25
2026-04-13Rodman David MalcomChief Medical OfficerOpen market sale 14,058$26.54
2026-04-13Congleton JonChief Executive OfficerOpen market sale 15,730$26.83
2026-04-09Rodman David MalcomChief Medical OfficerOption exercise 2,170$16.00
2026-04-09Rodman David MalcomChief Medical OfficerOpen market sale 2,170$27.38

Recent SEC filings

Official company reports and insider transaction filings. Form 4 reports a transaction; it does not by itself explain why it happened.

Source: SEC EDGAR submissions · updated 2026-11-02 15:29 UTC

FiledFormReport periodOfficial filing
2026-10-298-K2026-10-27 View on SEC.gov →
2026-10-2042026-10-19 View on SEC.gov →
2026-10-2042026-10-19 View on SEC.gov →
2026-10-198-K2026-10-16 View on SEC.gov →
2026-10-0242026-09-30 View on SEC.gov →
2026-09-2442026-09-22 View on SEC.gov →
2026-09-2242026-09-21 View on SEC.gov →
2026-09-1742026-09-15 View on SEC.gov →
2026-08-2542026-08-21 View on SEC.gov →
2026-08-1242026-08-10 View on SEC.gov →
2026-08-1242026-08-10 View on SEC.gov →
2026-08-1110-Q2026-06-30 View on SEC.gov →

Headlines about MLYS (Mineralys Therapeutics, Inc.). Links open the publisher — we don’t host full articles.

SEC filings ↓

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